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Nutrients 6 (2), 466488

The combination of arginine deprivation and 5-fluorouracil improves therapeutic efficacy in argininosuccinate synthetase negative hepatocellular carcinoma

PLoS One 11 , e0163214 (2016)

Innate immune activation in neurodegenerative disease

Each glutathione molecule contains one of each of these amino acids

For the non-interventional cohort, a group size of 20 subjects will detect a minimum difference in baseline GSH of at least 16% between young and elderly healthy subjects (0.05 alpha, 0.8 power) based on an inter-subject CV of 22%